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Poultry production in India is becoming popular day by day. India is the fourth largest producer of eggs in the world. The potential of the industry is such that an increase in the per capita consumption by one egg or 50 grams of poultry meat can create employment for about 25,000 people, Approximately, about one lakh people get direct and six lakh people get indirect employment from this sector. Poultry, in fact, has registered the maximum growth rate among all the sectors of agriculture. The annual contribution of the poultry section to the Gross national Product is about Rs. 7,810 crores. Poultry meat is the major meat consumed in India and has wider regional acceptance Diseases in poultry are major constraints to achieve desired profits. Present manuscript is an attempt to address this problem in holistic way to help farmers, entrepreneurs and practicing veterinarians in poultry production. Recent world outbreak of Bird flu has again emphasized that biosecurity is very important to fight against such infections.This book has special focus on all aspects of biosecurity at farms. Chapters in the book are arranged as per the etiology and systems affected. A special feature "Bus-stop" is introduced to refresh the knowledge about relevant issues related to poultry production. Recent developments related to Bird flu have been incorporated also. Alternative poultry species of national importance like Guinea fowls have been given special attention. In appendices, a matching table is specially prepared for quick and readymade way of diagnosing the disease in a bird. It is always advisable to contact skilled veterinarian for treatment. Right knowledge with hard work is the only key to success in poultry production. You may find best guidance from this innovative book. You may find best guidance from this innovative book. All efforts have been made to eradicate errors. But readers are requested to indicate the same, if any, to Author only. We are thankful to all well-wishers for their outstanding support.