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Synopsis In this interesting, at once absorbing and fascinating study, the author argues that both the physical resources and the intellectual tools needed to support scientific progress are approaching the limits of their viability; and as a result science may come to an end and merge with philosophy or may take some form of art. Discussing about all the major scientific theories discovered so far -- classical mechanics, thermodynamics, evolution, relativity, cosmology, unified theories and so on -- the author gives several reasons to show that they are all 'closed' theories. The new and different perspective on the future of science as offered in this volume should attract a wide range of readers including those who disagree with the author. N S Prasad works at Indian Space Research Organisation.