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In Vitro Experimental Pharmacology

Asmita Gajbhiye Patil (Author)

In context of drug discovery and development in vivo experimentation should be performed only if is necessary and well-conceived. Both from ethical and practical perspective, in vitro bioassays are more viable and efficacious in the preliminary pharmacological screening of a newly discovered drug molecule.

The book is conceptualized with the aim to be of value to both the experienced as well as the new researchers in biomedical sciences. The pharmacological domains discussed in the book are anti-inflammatory, antioxidant, antidiabetic, antimicrobial, antimalarial, antileshmanial and anticancer bioassays. Additionally the book begins by discussing the basic concepts governing experimental pharmacology and a chapter dealing with enzyme-based bioassays has also been incorporated. The assays described in the book include stepwise experimental procedure preceded with an explanation of the principal and theory governing the procedure.

The book attempts to be a useful blend of classical as well as neoclassical assays with modern instrumental techniques set out in a way that the researcher can assimilate readily the pharmacological spectrum of the test molecule and follow subsequently with further precise experimentation in animal model.

Contents: Preface. 1. Introduction to Experimental Pharmacology. 2. In vitro Anti-inflammatory Assay. 3. In vitro Antioxidant Assay. 4. In vitro Antidiabetic Assay. 5. In vitro Enzyme-Based Assay. 6. In vitro Antimicrobial Assay. 7. In vitro Assay for Tropical Disease. 8. In vitro Anticancer Assay. Index.

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Bibliographic information

Title In Vitro Experimental Pharmacology
Format Hardcover
Date published: 28.06.2019
Edition 1st ed.
Language: English
isbn 9789388178938
length 200p., 8 Color Plates.