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The first edition of Pharmacology: A Comprehensive Approach is a new book which covers many general and very important topics in Pharmacology. The book describes wide range of contents and it is divided into XVII sections comprising of 73 chapters and 5 Appendix. The various chapters present in this book contains wide range of topics and the authors have taken utmost care and consideration to enlighten and cover all important topics useful for all students in health sciences discipline. All the topics of the textbook are described in detail with several salient features covering mechanism of action, pharmacokinetics, adverse effects, therapeutic indications and drug interactions. This book is interspersed with tables and figures. This book will be an asset to all students of medical discipline since wide range of topics are covered.

Contents: I: General Principles: 1. Branches and Divisions of Pharmacology. 2. Pharmacokinetics of Drugs. 3. Drug Receptors and Pharmacodynamics. 4. Drug Biotransformation. II: Drugs Affecting Autonomic nervous System: 5. General Considerations of Autonomic Nervous System. 6. Cholinergic Drugs. 7. Muscarinic Receptor Blocking Drugs. 8. Adrenergic Drugs. 9. Adrenergic Blocking Drugs. 10. Ganglionic Stimulating and Blocking Agents. 11. Skeletal Muscle Relaxants. III: Drugs Affecting Central Nervous System: 12: General Considerations of Central Nervous System. 13. Neurodegenerative Diseases. 14. General Anaesthetics. 15. Sedative Hypnotics and Anxiolytic Drugs.16. Neuroleptics. 17. Antidepressants. 18. Antiepileptic Drugs. 19. Opioid Analgesics. 20. Non Steroidal Anti-inflammatory Drugs. 21. CNS Stimulants. 22. Drug Dependence and Drug Abuse. 23. Local Anaesthetics. IV: Drugs Affecting on Cardiovascular System: 24. Drugs Used in Heart Failure. 25. Antiarrhythmic Drugs. 26. Antianginal Drugs. 27. Antihypertensives. 28. Hypolipidemic Drugs. V. Drugs Affecting Haemostasis and Thrombosis: 29. Drugs and Blood Coagulation. 30. Hemopoietic Drugs and Plasma Volume Expanders. VI. Drugs Affecting Renal Function: 31. Diuretics and Antidiuretics. VII. Drugs Affecting Endocrine System: 32. Pituitary Hormones. 33. Thyroid, Parathyroid Hormones and Antithyroid Drugs. 34. Insulin and Oral Hypoglycemic Drugs. 35. Estrogens, Progestins and Androgens. 36. Adrenal Hormones. VIII. Drugs Affecting Respiratory Systems: 37. Drugs Used to Treat Asthma. 38. Drugs Used to Treat Allergic Rhinitis. 39. Drugs Used to Treat Cough, COPD and Cystic Fibrosism. IX. Drugs Affecting Gastrointestinal Tract: 40. Drugs Used to Treat Peptic, Ulcer Disease. 41. Drugs Used in Constipation. 42. Emetics and Antiemetic Drugs. 43. Drugs Used in Diarrhoea. 44. Digestants and GERD. X. Drugs Used for Other Therapies: 45. Drugs Used to Treat Erectile Dysfunction. 46. Drugs Used to Treat Osteoporosis. 47. Drugs Used to Treat Obesity. XI. Biogenic Amines and Polypeptides: 48. Histamine and Antihistamines. 49. 5-Hydroxytryptamine, its Agonists and Antagonists.50. Angiotensin, Kinins, Leukotrienes, Prostaglandins, Cytokines, Nitric Oxide and Platelet activating Factor Angiotensin. XII. Chemotherapeutic Drugs: 51. Sulfonamides, Trimethoprim and Cotrimoxazole. 52. Cell Wall Inhibitors. 53. Protein Synthesis Inhibitors. 54. Quinolones and Urinary Antiseptics. 55. Antimycobacterials. 56. Antifungal Drugs. 57. Antiprotozoal Drugs. 58. Anthelmintic Drugs. 59. Antiviral Drugs. 60. Anticancer Drugs. XIII. Drugs Used in Skin and Eye Disorders: 61. Antiseptics and Disinfectants. 62. Drugs Used to Treat Glaucoma. 63. Drugs Used to Treat Psoriasis and Acne Vulgaris. XIV: Toxicology: 64. Introduction to Toxicology. 65. Heavy Metal Intoxication and Chelators. XV. Miscellaneous: 66. Management of the Poisoned Patient. 67. Drugs Used to Treat Rheumatoid Arthritis and Gout, 68. Drugs that Affect Uterine Function. 69. Immunosuppressants and Immunostimulants. 70. Vitamins, Minerals and Antioxidants. 71. Drug Therapy in Pregnancy. 72. Drugs Use during Lactation. XVI. Pharmacology Gate and GPAT Previous Questions: 74. Multiple Choice, Linked and Match the Following Questions of Previous GATE and GPAT Examinations along with Answers. Appendices.