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There exists tremendous knowledge in ancient Indian scriptures on traditional systems of medicine regarding liver disorders, their management and cure. The Indian Council of Medical Research initiated a programme under which the relevant knowledge and scientific data has been searched from the available literature and integrated in the present monograph. It provides an insight of the liver and its disorders from the point of view of Ayuveda, Unani and Allopathic systems of medicines, rational use of plant drugs of traditional Indian systems of medicine, and a systematic and planned evolution of plant drugs. It also contains in depth information on various aspects of twelve most important medicinal plants with all the scientific works done on hepatoprotective activity and their use in traditional systems of medicine. A set of indices on Medicinal Plants (botanical name with authority), Chemical Constituents, Classical Ayurvedic Formulations, Other names of plants, is also included.