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Synopsis 'Surface Marking of Keynotes' is a new and very interesting method of studying materia medica. Every possible attempt has been made to present the individualistic features of every drug to make the study interesting and within easy grasp. In this book three different colour dots (red, blue, green) are marked on the body surface to denote the location and gradation of symptoms covered by that particular drug. In this way we can easily frame a picture or get an impression in our mind about that drug regarding which part of body is most affected by it and in which intensity it is affected. Drug symptoms are written opposite to the body sketch on one side of the book. Only most striking, characteristic, peculiar, uncommon, very important and clinical symptoms are taken in each drug. Symptoms are arranged preferably according to their clinical importance under three grades and not in an anatomical order. It makes the study of materia medica extremely interesting and also lowers the burden of memorizing the full pathogenesity of each drug.